Genomics:GTL (formerly Genomes to Life) is a program of the Office of Biological and Environmental Research (sponsors of the Human Genome Project). A comprehensive approach to understanding entire biological systems must encompass genes and proteins, multimolecular assemblies (“molecular machines”), pathways and interacting networks, whole cells, communities of cells, and environments. Surmounting the technical challenges presented by these multiscale explorations is a daunting prospect that will require dramatic improvements in research performance, throughput, quality, and cost. New capabilities also will be needed in computation, modeling, and simulation, which are integral parts of systems biology research. Obtaining a predictive understanding of living systems requires analyses of great scale and complexity. [Systems Engineering tools used to reverse engineer complex system designs.]
Systems Biology - Application of human design systems engineering tools prove surprisingly effective on biology. Design tools are required to understand and reverse engineer living systems. Function and form of design are observed and used to understand the complexity of biological systems much like reverse engineering. Science disciplines of biology, chemistry, physics, computation, mathematics, and medicine are integrated for the analysis of life.
I Systems Biology
Systems Biology Institute
Systems Biology at PNNL - Pacific Northwest National Laboratory
Systems Biology - 5 Components
Molecular Manufacturing - What happens when nanotechnology becomes indistinguishable from biology? One is clearly designed and the other not? Can nanotechnology arise spontaneously without intelligence?